Role of aquaporin water channels in kidney and lung
AS Verkman - The American journal of the medical sciences, 1998 - Elsevier
Several aquaporin-type water channels are expressed in mammalian kidney and lung:
AQP1 in lung microvessels and kidney proximal tubule, thin descending limb of Henle, and
vasa recta; AQP2 in apical membrane of collecting duct epithelium; AQP3 and AQP4 in
basolateral membranes of airway and collecting duct epithelium; and AQP5 in alveolar
epithelium. Novel quantitative fluorescence methods demonstrated very high water
permeabilities of the alveolar epithelial and endothelial barriers, and moderately high water …
AQP1 in lung microvessels and kidney proximal tubule, thin descending limb of Henle, and
vasa recta; AQP2 in apical membrane of collecting duct epithelium; AQP3 and AQP4 in
basolateral membranes of airway and collecting duct epithelium; and AQP5 in alveolar
epithelium. Novel quantitative fluorescence methods demonstrated very high water
permeabilities of the alveolar epithelial and endothelial barriers, and moderately high water …
