[HTML][HTML] Adipocyte low density lipoprotein receptor-related protein gene expression and function is regulated by peroxisome proliferator-activated receptor γ

A Gauthier, G Vassiliou, F Benoist… - Journal of Biological …, 2003 - ASBMB
The α 2-macroglobulin receptor/low density lipoprotein receptor-related protein (LRP) is a
large multifunctional receptor that interacts with a variety of molecules. It is implicated in
biologically important processes such as lipoprotein metabolism, neurological function,
tissue remodeling, protease complex clearance, and cell signal transduction. However, the
regulation of LRP gene expression remains largely unknown. In this study, we have
analyzed 2 kb of the 5′-flanking region of the LRP gene and identified a predicted …