Further study of the genetic toxicity of gentian violet
W Au, MA Butler, SE Bloom, TS Matney - Mutation Research/Genetic …, 1979 - Elsevier
The genetic toxicity of gentian violet was studied with the Ames and the Rosenkranz
bacterial assays as well as the cytogenetic assays (Chinese hamster ovary cells in vitro in
the presence of rat-liver S-9 fractions, the chicken-embryo and mouse-bone-marrow cells in
vivo). Gentian violet was found to be toxic but not mutagenic in the Ames assay. however, it
was active in the Rosenkranz assay causing reparable DNA damage. The presence of S-9
in the in vitro cytogenetic assay and in the bacterial assays showed that the activity of …
bacterial assays as well as the cytogenetic assays (Chinese hamster ovary cells in vitro in
the presence of rat-liver S-9 fractions, the chicken-embryo and mouse-bone-marrow cells in
vivo). Gentian violet was found to be toxic but not mutagenic in the Ames assay. however, it
was active in the Rosenkranz assay causing reparable DNA damage. The presence of S-9
in the in vitro cytogenetic assay and in the bacterial assays showed that the activity of …
