Human IgE antibody serology: a primer for the practicing North American allergist/immunologist
RG Hamilton, PB Williams - Journal of allergy and clinical immunology, 2010 - Elsevier
The allergist/immunologist judiciously diagnoses allergic disease by using confirmatory IgE
antibody data from in vivo and in vitro assays after the collection of a clinical history. After an
overview of historical events, clinically available allergen-specific IgE assays from Phadia,
Siemens, and Hycor are contrasted by their design and performance characteristics. The
assays share comparable working ranges, analytical sensitivities, and excellent precision,
reproducibility, and linearity to a performance standard of< 15% coefficients of variation …
antibody data from in vivo and in vitro assays after the collection of a clinical history. After an
overview of historical events, clinically available allergen-specific IgE assays from Phadia,
Siemens, and Hycor are contrasted by their design and performance characteristics. The
assays share comparable working ranges, analytical sensitivities, and excellent precision,
reproducibility, and linearity to a performance standard of< 15% coefficients of variation …