Viral and clinical factors associated with the fulminant course of hepatitis A infection
G Rezende, AM Roque-Afonso, D Samuel, M Gigou… - Hepatology, 2003 - Elsevier
Fulminant hepatitis is a severe complication of hepatitis A virus infection. Its mechanism is
unknown. Liver transplantation can be necessary, but spontaneous recovery is frequent.
There are no data on the level of viral replication according to the clinical form of hepatitis A.
We reviewed the files of 50 patients with acute hepatitis A. Nineteen patients had fulminant
hepatitis (defined by encephalopathy and factor V< 50%), and, from them, 10 patients
underwent transplantation. Hepatitis A virus (HAV) RNA was quantified by real-time PCR on …
unknown. Liver transplantation can be necessary, but spontaneous recovery is frequent.
There are no data on the level of viral replication according to the clinical form of hepatitis A.
We reviewed the files of 50 patients with acute hepatitis A. Nineteen patients had fulminant
hepatitis (defined by encephalopathy and factor V< 50%), and, from them, 10 patients
underwent transplantation. Hepatitis A virus (HAV) RNA was quantified by real-time PCR on …
