[PDF][PDF] Effects of anti-IgE mAb on serum IgE, FceRII/CD23 expression on splenic B cells and worm burden in mice infected with Paragonimus westermani
MH Shin, HK Min - Kor J Parasitol, 1997 - parasitol.kr
It is generally accepted that parasite—specific IgE plays a crucial role in host defense
against helminthic parasites. However. the role of high levels of nonspecific IgE in helminthic
infections is still controversial. To investigate the role of nonspecific IgE in primary infections
with P. westemiant, the effect of anti—IgE mAb treatment on serum IgE, FceRII/CD23
expression and worm burden in Paragonimus-infected mice were examined. In mice treated
with anti—IgE antibody, the total IgE levels were not detectable [l [lg/ml} throughout the …
against helminthic parasites. However. the role of high levels of nonspecific IgE in helminthic
infections is still controversial. To investigate the role of nonspecific IgE in primary infections
with P. westemiant, the effect of anti—IgE mAb treatment on serum IgE, FceRII/CD23
expression and worm burden in Paragonimus-infected mice were examined. In mice treated
with anti—IgE antibody, the total IgE levels were not detectable [l [lg/ml} throughout the …
