The role of complement in inflammation during experimental pneumococcal meningitis
E Tuomanen, B Hengstler, O Zak, A Tomasz - Microbial pathogenesis, 1986 - Elsevier
The mechanism whereby an effective bactericidal inflammatory reaction develops in the
subarachnoid space is not clearly defined. While normal cerebrospinal fluid is deficient in
complement, immunoglobulin and leukocytes, these serum components appear in
cerebrospinal fluid (CSF) during the course of bacterial meningitis. Using a rabbit model of
pneumococcal meningitis we examined the role of the alternate complement pathway in
three early events important to the defense of the subarachnoid space: leukocyte …
subarachnoid space is not clearly defined. While normal cerebrospinal fluid is deficient in
complement, immunoglobulin and leukocytes, these serum components appear in
cerebrospinal fluid (CSF) during the course of bacterial meningitis. Using a rabbit model of
pneumococcal meningitis we examined the role of the alternate complement pathway in
three early events important to the defense of the subarachnoid space: leukocyte …