Evidence of extraordinary growth in the progressive enlargement of renal cysts
JJ Grantham, LT Cook, LH Wetzel… - Clinical Journal of the …, 2010 - journals.lww.com
Background and objectives: In autosomal dominant polycystic kidney disease, cysts derived
from tubules are detected at birth by ultrasound (threshold for detection> 7.0 mm); thus, fetal
cyst growth rates must exceed 2300%/yr. In adults, the combined renal cyst component
enlarges at approximately 12%/yr by growth of individual cysts. To explore this discrepancy,
the growth rates of individual cysts were determined in adult polycystic kidneys.
from tubules are detected at birth by ultrasound (threshold for detection> 7.0 mm); thus, fetal
cyst growth rates must exceed 2300%/yr. In adults, the combined renal cyst component
enlarges at approximately 12%/yr by growth of individual cysts. To explore this discrepancy,
the growth rates of individual cysts were determined in adult polycystic kidneys.