Asymptomatic autoantibodies associate with future anti-glomerular basement membrane disease
SW Olson, CB Arbogast, TP Baker… - Journal of the …, 2011 - journals.lww.com
The pathophysiology of anti-glomerular basement membrane (anti-GBM) disease before
clinical presentation is unknown. The presence of anti-GBM, anti-proteinase 3 (PR3), and
anti-myeloperoxidase (MPO) antibodies associate with the disease at the time of diagnosis,
but little is known about the presence of these autoantibodies before diagnosis. We used
serum samples from the Department of Defense Serum Repository to conduct a case-control
study involving 30 patients diagnosed with anti-GBM disease and 30 healthy controls …
clinical presentation is unknown. The presence of anti-GBM, anti-proteinase 3 (PR3), and
anti-myeloperoxidase (MPO) antibodies associate with the disease at the time of diagnosis,
but little is known about the presence of these autoantibodies before diagnosis. We used
serum samples from the Department of Defense Serum Repository to conduct a case-control
study involving 30 patients diagnosed with anti-GBM disease and 30 healthy controls …