Expression of bFGF, KGF and FGF receptors on normal oral mucosa and SCC

M Partridge, S Kiguwa, Y Luqmani… - European Journal of …, 1996 - Elsevier
Fibroblast growth factors (FGFs) are involved in the transmission of signals between the
epithelia and connective tissue, and influence epidermal growth and differentiation. They
are thought to be important in the restoration of normal tissues after injury and aberrant
expression may also play a role in tumorigenesis. However, no information is available on
the nature of cells within oral mucosa which synthesise and/or respond to FGFs. We have
screened normal oral mucosa and oral squamous cell carcinoma (SCC) for expression of …