Achieving complete understanding of any living thing inevitably requires thorough analysis
of both its anatomic and dynamic properties. Live-cell imaging experiments carried out to
this end often produce massive amounts of time-lapse image data containing far more
information than can be digested by a human observer. Computerized image analysis offers
the potential to take full advantage of available data in an efficient and reproducible manner.
A recurring task in many experiments is the tracking of large numbers of cells or particles …