5-Methylcytosine in eukaryotic DNA
M Ehrlich, RYH Wang - Science, 1981 - science.org
M Ehrlich, RYH Wang
Science, 1981•science.orgA small portion of the cytosine residues in the DNA of higher eukaryotes as well as in that of
many lowe eukaryotes if methylated. The resulting 5-methylcytosine residues occur in
specific in the DNA, usually adjacent to guanine residues on the 3'side. This methylation of
eukaryotic DNA has been proposed to function in many ways, including control of
transcription, maintenance of chromosome structure, repair of DNA, establishment of
preferred sites for mutation, oncogenic transformation, and, in certain systems, protection of …
many lowe eukaryotes if methylated. The resulting 5-methylcytosine residues occur in
specific in the DNA, usually adjacent to guanine residues on the 3'side. This methylation of
eukaryotic DNA has been proposed to function in many ways, including control of
transcription, maintenance of chromosome structure, repair of DNA, establishment of
preferred sites for mutation, oncogenic transformation, and, in certain systems, protection of …
A small portion of the cytosine residues in the DNA of higher eukaryotes as well as in that of many lowe eukaryotes if methylated. The resulting 5-methylcytosine residues occur in specific in the DNA, usually adjacent to guanine residues on the 3' side. This methylation of eukaryotic DNA has been proposed to function in many ways, including control of transcription, maintenance of chromosome structure, repair of DNA, establishment of preferred sites for mutation, oncogenic transformation, and, in certain systems, protection of DNA against enzymatic degradation.
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