[HTML][HTML] Epigallocatechin Gallate (EGCG) Stimulates Autophagy in Vascular Endothelial Cells: A POTENTIAL ROLE FOR REDUCING LIPID ACCUMULATION*♦

HS Kim, V Montana, HJ Jang, V Parpura… - Journal of Biological …, 2013 - ASBMB
Epigallocatechin gallate (EGCG) is a major polyphenol in green tea that has beneficial
effects in the prevention of cardiovascular disease. Autophagy is a cellular process that
protects cells from stressful conditions. To determine whether the beneficial effect of EGCG
is mediated by a mechanism involving autophagy, the roles of the EGCG-stimulated
autophagy in the context of ectopic lipid accumulation were investigated. Treatment with
EGCG increased formation of LC3-II and autophagosomes in primary bovine aortic …