Neuronal restricted progenitors (NRPs) represent a type of transitional intermediate cells
that lie between multipotent neural progenitors and terminal differentiated neurons during
neurogenesis. These NRPs have the ability to self-renew and differentiate into neurons, but
not into glial cells, which is considered an advantage for cellular therapy of human
neurodegenerative diseases. However, difficulty in the extraction of highly purified NRPs
from normal nervous tissue prevents further studies and applications. In this study, we report …