Migration and multipotentiality of PSA-NCAM+ neural precursors transplanted in the developing brain

S Vitry, V Avellana-Adalid, F Lachapelle… - Molecular and Cellular …, 2001 - Elsevier
By optimizing the previously described strategy for obtention of spheres enriched in PSA-
NCAM+ precursors, we prepared PSA-NCAM-immunoselected cell populations from
cerebral hemispheres of neonatal MBP-LacZ transgenic mice. These cells expressed
Nestin, exhibited clonal expansion potential and formed spheres, which were initially
enriched in PSA-NCAM+ cells but became enriched in GD3+ oligodendrocyte progenitors
after 1 week in B104 contionned medium. One month after their periventricular …