Antiretroviral drugs constitute a milestone in the treatment of human immunodeficiency virus
(HIV) infection; however, emerging problems limit their long-term use, and an increasing
number of patients interrupt the prescribed continuous drug therapy for short or long periods.
Some patients appear to benefit from structured treatment interruptions (STI), involving
monitored repetition of on-and-off cycles of drugs; however, it is unclear whether patients
and/or physicians should consider STI as a treatment option. This review is intended to …