A polymorphism in the ABCG1 promoter is functionally associated with coronary artery disease in a Chinese Han population

Y Xu, W Wang, L Zhang, LP Qi, LY Li, LF Chen, Q Fang… - Atherosclerosis, 2011 - Elsevier
OBJECTIVE: In this study, we examine the association of single nucleotide polymorphisms
(SNPs) of the human ATP binding cassette transporter G1 (ABCG1) gene with
atherosclerotic coronary artery disease (CAD) in a Chinese Han population. METHODS:
1021 patients with CAD and 1013 unaffected control subjects were enrolled. PCR-based
ligation detection reaction (PCR-LDR) method was used to genotype four SNPs of ABCG1,
three (rs2234714, rs2234715 and rs57137919) in the promoter region and one (rs1044317) …