Natural killer cells: from innate to adaptive features
AM Mujal, RB Delconte, JC Sun - Annual review of immunology, 2021 - annualreviews.org
AM Mujal, RB Delconte, JC Sun
Annual review of immunology, 2021•annualreviews.orgNatural killer (NK) cells are innate lymphocytes that provide critical host defense against
pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells
have been recognized over the last decade for their ability to undergo adaptive immune
processes, including antigen-driven clonal expansion and generation of long-lived memory.
This review presents an overview of how NK cells lithely partake in both innate and adaptive
responses and how this versatility is manifest in human NK cell–mediated immunity.
pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells
have been recognized over the last decade for their ability to undergo adaptive immune
processes, including antigen-driven clonal expansion and generation of long-lived memory.
This review presents an overview of how NK cells lithely partake in both innate and adaptive
responses and how this versatility is manifest in human NK cell–mediated immunity.
Natural killer (NK) cells are innate lymphocytes that provide critical host defense against pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells have been recognized over the last decade for their ability to undergo adaptive immune processes, including antigen-driven clonal expansion and generation of long-lived memory. This review presents an overview of how NK cells lithely partake in both innate and adaptive responses and how this versatility is manifest in human NK cell–mediated immunity.
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