[HTML][HTML] Precision surgery and kidney cancer: knowledge of genetic alterations influences surgical management

PT Gomella, WM Linehan, MW Ball - Genes, 2021 - mdpi.com
Genes, 2021mdpi.com
Renal cell carcinoma is a term that represents multiple different disease processes, each
driven by different genetic alterations, with distinct histology, and biological potential which
necessitates divergent management strategies. This review discusses the genetic
alterations seen in several forms of hereditary kidney cancer and how that knowledge can
dictate when and how to intervene with a focus on the surgical management of these tumors.
Renal cell carcinoma is a term that represents multiple different disease processes, each driven by different genetic alterations, with distinct histology, and biological potential which necessitates divergent management strategies. This review discusses the genetic alterations seen in several forms of hereditary kidney cancer and how that knowledge can dictate when and how to intervene with a focus on the surgical management of these tumors.
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