[HTML][HTML] The renin–angiotensin system: An integrated view of lung disease and coagulopathy in COVID-19 and therapeutic implications
B Diamond - Journal of Experimental Medicine, 2020 - rupress.org
B Diamond
Journal of Experimental Medicine, 2020•rupress.orgThe renin–angiotensin system (RAS) has long been appreciated as a major regulator of
blood pressure, but has more recently been recognized as a mechanism for modulating
inflammation as well. While there has been concern in COVID-19 patients over the use of
drugs that target this system, the RAS has not been explored fully as a druggable target. The
abbreviated description of the RAS suggests that its dysregulation may be at the center of
COVID-19.
blood pressure, but has more recently been recognized as a mechanism for modulating
inflammation as well. While there has been concern in COVID-19 patients over the use of
drugs that target this system, the RAS has not been explored fully as a druggable target. The
abbreviated description of the RAS suggests that its dysregulation may be at the center of
COVID-19.
The renin–angiotensin system (RAS) has long been appreciated as a major regulator of blood pressure, but has more recently been recognized as a mechanism for modulating inflammation as well. While there has been concern in COVID-19 patients over the use of drugs that target this system, the RAS has not been explored fully as a druggable target. The abbreviated description of the RAS suggests that its dysregulation may be at the center of COVID-19.
rupress.org