Renal lesions predict progression of diabetic nephropathy in type 1 diabetes
ML Caramori, A Parks, M Mauer - Journal of the American Society …, 2013 - journals.lww.com
Whether early glomerular, tubulointerstitial, vascular, and global glomerulosclerotic lesions
can predict progression of diabetic nephropathy is not well defined. Here, we sought to
determine whether renal structural parameters predict the development of proteinuria or
ESRD after long-term follow-up. We measured several renal structures in kidney biopsies
from 94 normoalbuminuric patients with longstanding type 1 diabetes using unbiased
morphometric methods. Greater width of the glomerular basement membrane and higher …
can predict progression of diabetic nephropathy is not well defined. Here, we sought to
determine whether renal structural parameters predict the development of proteinuria or
ESRD after long-term follow-up. We measured several renal structures in kidney biopsies
from 94 normoalbuminuric patients with longstanding type 1 diabetes using unbiased
morphometric methods. Greater width of the glomerular basement membrane and higher …